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class="sm1">Definitions</a></td></tr> <tr><td colspan="2"><img src="images/blank.gif" border="0" width="1" height="2"></img></td></tr> <tr bgcolor="#4EAFAF" class="size"><td >&nbsp;</td><td><a href="links.html" class="sm1">Links</a></td></tr> </table> </td> </tr> </table> </div> <!--/leftnav--> </td> <td width="45"><img src="images/transparent.gif" width="45" height="1" alt="" /></td> <td width="620" valign="top"><a name="main"></a> <!--pagecontent--> <div name="Research"> <table cellspacing="0" cellpadding="0" border="0" width="100%"> <tr> <td> <table cellspacing="0" cellpadding="0" border="0" width="100%"> <tr><td> <span class="red">Research</span><br /> <br /> </td></tr> <tr><td><span class="blue">Key Research Results</span><br /> (<i>Click highlighted text to view papers</i>)<br /><br /> <a href="http://www.ncbi.nlm.nih.gov/pubmed/19280657">Rushlow D, Piovesan B, Zhang K, Prigoda-Lee NL, Marchong MN, Clark RD, Gallie BL.</a> Detection of mosaic RB1 mutations in families with retinoblastoma. <i>Hum Mutat.</i> 2009 May;<b>30</b>(5):842-51<br /><br /> <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18181215">Zhang E, Nowak I, Rushlow D, Gallie BL, Lohmann DR</a>. Patterns of missplicing caused by <i>RB1</i> gene mutations in patients with retinoblastoma and association with phenotypic expression. <i>Human Mutation</i> 2008 Apr <b>29</b>(4):475-84.<br /><br /> <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12541220&dopt=Abstract">Richter S, Vandezande K, Chen N, Zhang K, Sutherland J, Anderson J, Han L, Panton R, Branco P, Gallie B.</a> Sensitive and efficient detection of RB1 gene mutations enhances care for families with retinoblastoma. <i>Am J Hum Genet</i>. 2003 Feb;<b>72</b>(2):253-69.<br /><br /> <a href="papers/NooraniAJHG1996.pdf">Noorani HZ, Khan HN, Gallie BL, Detsky AS.</a> Cost comparison of molecular versus conventional screening of relatives at risk for retinoblastoma. <i>Am J Hum Genet</i>. 1996 Aug; <b>59</b>(2):301-7.<br /><br /> </td></tr> <tr> <td><br /> <a name="Brenda"></a><span class="blue">Brenda Gallie - Selected Research</span><br /> Click <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=PureSearch&db=PubMed&details_term=gallie%20B%5Bau%5D" target="_blank" ONCLICK="window.open('http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=PureSearch&db=PubMed&details_term=gallie%20B%5Bau%5D', 'popup', 'width=800,height=600,resizable=yes,scrollbars=yes'); return false">here</a> for complete PubMed listing.<br /><br /> <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10966849&dopt=Abstract"> DiCiommo D, Gallie BL, Bremner R.</a> Retinoblastoma: the disease, gene and protein provide critical leads to understand cancer. <i>Semin Cancer Biol.</i> 2000 Aug;<b>10</b>(4):255-69.<br /><br /></td></tr> <tr> <td> <br /><a name="Beata"></a><span class="blue">Beata Piovesan - Selected Research</span><br /> Click <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=PureSearch&db=PubMed&details_term=(Piovesan%20B%5Bau%5D%20OR%20Kuzniar%20B%5Bau%5D%20)%20AND%20(1991%5BPDat%5D%20:%203000%5BPDat%5D)" target="_blank" ONCLICK="window.open('http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=PureSearch&db=PubMed&details_term=(Piovesan%20B%5Bau%5D%20OR%20Kuzniar%20B%5Bau%5D%20)%20AND%20("1991"%5BPDat%5D%20:%20"3000"%5BPDat%5D)', 'popup', 'width=800,height=600,resizable=yes,scrollbars=yes'); return false">here</a> for complete PubMed listing. <br /><br /> <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9811465&dopt=Abstract"> Piovesan B, Pennell N, Berinstein NL.</a> Human lymphoblastoid cell lines expressing mutant p53 exhibit decreased sensitivity to cisplatin-induced cytotoxicity. <i>Oncogene</i>. (1998 Nov 5) <b>17</b>(18):2339-50. <br /><br /></td></tr> <tr><td> <br /><a name="Nadia"></a><span class="blue">Nadia Prigoda-Lee - Selected Research</span><br /> Click <a href="http://eutils.ncbi.nlm.nih.gov/entrez/eutils/erss.cgi?rss_guid=10cYQ8mUsB6j5iB31FYldS6vfaeAl_xjf8x503m804L6UzbsxZ">here</a> for complete PubMed listing <br /><br /> <a href="papers/PrigodaMolBioEvo2005.pdf">Prigoda NL, Nassuth A, Mable BK.</a> Phenotypic and genotypic expression of self-incompatibility haplotypes in <i>Arabidopsis lyrata</i> suggests unique origin of alleles in different dominance classes. <i>Molecular Biology and Evolution</i> <b>22</b>, 7, 1609-20. <br /><br /></td></tr> <tr><td> <br /><a name="Diane"></a><span class="blue">Diane Rushlow - Selected Research</span><br /> <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10380769&dopt=Abstract"> Yager TD, Baron L, Batra R, Bouevitch A, Chan D, Chan K, Darasch S, Gilchrist R, Izmailov A, Lacroix JM, Marchelleta K, Renfrew J, Rushlow D, Steinbach E, Ton C, Waterhouse P, Zaleski H, Dunn JM, Stevens J.</a> High performance DNA sequencing, and the detection of mutations and polymorphisms, on the Clipper sequencer. <i>Electrophoresis</i>. 1999 Jun; <b>20</b>(6):1280-300. <br /><br /> <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9326321"> Bremner R, Du DC, Connolly-Wilson MJ, Bridge P, Ahmad KF, Mostachfi H, Rushlow D, Dunn JM, Gallie BL.</a> Deletion of RB exons 24 and 25 causes low-penetrance retinoblastoma. <i> Am J Hum Genet.</i> 1997 Sep; <b>61</b>(3):556-70. <br /><br /></td></tr> </table> </td></tr></table> </div> </td> </tr> </table> <!--/pagecontent--> <!--/mainbody--> <!--footer--> <!-- print page, hide navigation options --> <div id="footer"> <table align="center" border="0" cellspacing="0" cellpadding="0"> <tr> <td width="100">&nbsp;</td> <td colspan="10"><hr size="1"></hr></td> </tr> <tr> <td width="140">&nbsp;</td> <td><a href="index.html" class="footlink">Home</a></td> <td><span class="separat">&nbsp;|&nbsp;</span></td> <td><a href="aboutus.html" class="footlink">About us</a></td> <td><span class="separat">&nbsp;|&nbsp;</span></td> <td><a href="retinob.html" class="footlink">Retinoblastoma</a></td> <td><span class="separat">&nbsp;|&nbsp;</span></td> <td><a href="rbgene.html" class="footlink"><i>RB1</i> gene testing</a></td> <td><span class="separat">&nbsp;|&nbsp;</span></td> <td><a href="submsamp.html" class="footlink">Submitting samples</a></td> </tr> </table> <table align="center" border="0" cellspacing="0" cellpadding="0"> <tr> <td width="120">&nbsp;</td> <td><a href="families.html" class="footlink">Info for families</a></td> <td><span class="separat">&nbsp;|&nbsp;</span></td> <td><a href="specials.html" class="footlink">Info for clinicians</a></td> <td><span class="separat">&nbsp;|&nbsp;</span></td> <td><a href="research.html" class="footlink">Research</a></td> <td><span class="separat">&nbsp;|&nbsp;</span></td> <td><a href="definiti.html" class="footlink">Definitions</a></td> <td><span class="separat">&nbsp;|&nbsp;</span></td> <td><a href="links.html" class="footlink">Links</a></td> <td><span class="separat">&nbsp;|&nbsp;</span></td> <td><a href="contact.html" class="footlink">Contact Us</a></td> <td><span class="separat">&nbsp;|&nbsp;</span></td> <td><a href="javascript:openwindowlink('sitemap.html')" class="footlink">Site map</a></td> </tr> </table> </div> <!--/footer--> </body> </html>